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Researchers find evidence of protein folding at site of  intracellular droplets

Researchers find evidence of protein folding at site of intracellular droplets

Author: Jessica Sieff

In a study published in the journal Chemical Science, researchers at the University of Notre Dame found that elevated concentrations of proteins within the droplets triggered a folding event, increasing the potential for protein aggregation — or misfolding — which has been linked to neurological diseases including Alzheimer’s disease and amyotrophic lateral sclerosis (ALS).

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Gregory Hartland Receives Prestigious American Chemical Society Award

Gregory Hartland Receives Prestigious American Chemical Society Award

Author: Rebecca Hicks

Gregory Hartland, Professor of Chemistry & Biochemistry at the University of Notre Dame, is the 2021 recipient of the American Chemical Society Division of Physical Chemistry Award in Experimental Physical Chemistry. Together with the Kuno group at the University of Notre Dame, the Hartland group has also recently developed a super-resolution IR imaging scheme...

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CDC publishes paper describing Notre Dame’s successful response to early surge in COVID-19 cases on campus

CDC publishes paper describing Notre Dame’s successful response to early surge in COVID-19 cases on campus

Author: Dennis Brown

The report details the University’s preparation for the return of students in August for in-person learning, the dramatic increase in cases during the first 10 days of classes, the decision to keep students on campus but to restrict interaction and teach only online for two weeks, and the robust mitigation measures taken that allowed a resumption of in-person learning after the pause.

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Hildreth to serve as interim dean, McDowell as interim associate dean of research in the College of Science

Hildreth to serve as interim dean, McDowell as interim associate dean of research in the College of Science

Michael Hildreth, associate dean of research in the College of Science at the University of Notre Dame, will serve as interim dean of the College of Science beginning January 1, 2021. That day, Mary Ann McDowell, associate professor in the Department of Biological Sciences, will begin serving as interim associate dean of research in the college.

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Science and Engineering Scholars Program propels students to success

Science and Engineering Scholars Program propels students to success

“This program is, wow,” said Chelsea Popoola, a math major who plans to attend medical school. The small classes allowed her to learn the material in a tight-knit environment. “I wish I had better words to explain how much this program has done for me. Whenever we need help with anything, there are many people willing to help.”

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Notre Dame launches “Consider This!” a weekly webinar series discussing COVID-19

Notre Dame launches “Consider This!” a weekly webinar series discussing COVID-19

Author: Brandi Wampler

Starting in October, each Monday from 6 to 7 p.m. EST, coronavirus experts will discuss a new aspect or angle of the pandemic, such as epidemiology, food security, public health, racial inequities, testing, vaccines, and evidence used to inform decisions about opening schools, athletics, and businesses. 

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How T-cell targets look in three dimensions may facilitate new cancer vaccines

How T-cell targets look in three dimensions may facilitate new cancer vaccines

T-cells, which hunt for traces of disease within other cells, work by identifying fragments of outsider proteins on a diseased cell’s surface and then go in for the literal kill.

With cancer, some of the mutated fragments of outsider proteins, called neoepitopes, can be recognized by T-cells and are ideal candidates for cancer vaccines. Unfortunately, those candidates are difficult to predict from genetic data alone.

 

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