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Researchers show how early RNA-based life may have repaired its genome, providing insight into the origins of life

Researchers show how early RNA-based life may have repaired its genome, providing insight into the origins of life

In a study published in Nature Communications, Saurja DasGupta, a biochemist at the University of Notre Dame, and colleagues present a key mechanism for sustaining RNA-based life: an engineered enzyme that selectively recognizes and repairs broken RNA.

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Study reveals how bacteria assemble their envelope

Study reveals how bacteria assemble their envelope

Red protein molecule interacting with a blue helical structure and a white polymer chain, showing a luminous binding site.
The protein PA2854 (shown in red) in Pseudomonas aeruginosa links the outer-membrane protein OprI (shown in blue) to the cell wall (depicted in white), a process that is necessary for the health of the bacterium. (Graphic provided by the Mobashery Lab)

Researchers at the University of Notre Dame and collaborators have discovered a key process for how the outer membrane of gram-negative bacteria attaches to the cell wall, advancing the understanding of how these bacteria frequently manifest resistance to antibiotics.

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First comprehensive look at breast cancer in Native American women reveals key genetic differences

First comprehensive look at breast cancer in Native American women reveals key genetic differences

Author: Brandi Wampler

Researchers from the University of Notre Dame have published the first known detailed study of breast cancer tissue from Native American women. The study, published in npj Precision Oncology, reveals important molecular differences that may impact the efficacy of therapies for female, Native American breast cancer patients.

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