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Science and Engineering Scholars Program propels students to success

Science and Engineering Scholars Program propels students to success

“This program is, wow,” said Chelsea Popoola, a math major who plans to attend medical school. The small classes allowed her to learn the material in a tight-knit environment. “I wish I had better words to explain how much this program has done for me. Whenever we need help with anything, there are many people willing to help.”

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WFCDD RFA Request for Applications-Now Open

The Warren Center for Drug Discovery invites new proposals for projects that are associated with drug discovery. In particular, projects associated with small molecule synthesis (libraries or molecular probes), hit validation, lead optimization, mid-sized scale up, assay development, protein purification, and ADMET screening. Any disease areas will be considered. Collaborative opportunities exist for the preparation of small molecules and/or computational-derived drug discovery via three cores: Chemical Synthesis & Drug Discovery, Computer-Aided Molecular Design, or Biological Screening and Development core. …

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Notre Dame launches “Consider This!” a weekly webinar series discussing COVID-19

Notre Dame launches “Consider This!” a weekly webinar series discussing COVID-19

Author: Brandi Wampler

Starting in October, each Monday from 6 to 7 p.m. EST, coronavirus experts will discuss a new aspect or angle of the pandemic, such as epidemiology, food security, public health, racial inequities, testing, vaccines, and evidence used to inform decisions about opening schools, athletics, and businesses. 

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How T-cell targets look in three dimensions may facilitate new cancer vaccines

How T-cell targets look in three dimensions may facilitate new cancer vaccines

T-cells, which hunt for traces of disease within other cells, work by identifying fragments of outsider proteins on a diseased cell’s surface and then go in for the literal kill.

With cancer, some of the mutated fragments of outsider proteins, called neoepitopes, can be recognized by T-cells and are ideal candidates for cancer vaccines. Unfortunately, those candidates are difficult to predict from genetic data alone.

 

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Francis Castellino Receives 2020 ISTH Esteemed Career Award

Francis Castellino Receives 2020 ISTH Esteemed Career Award

Author: Mary Prorok

 

Francis J. Castellino

Francis J. Castellino, Kleiderer-Pezold Professor of Biochemistry and Director of the W.M. Keck Center for Transgene Research, has been selected as a recipient of the 2020 International Society on Thrombosis and Haemostasis (ISTH) Esteemed Career Award. This prestigious award is given to those who “have made significant contributions to the understanding, treatment and diagnosis, research and education in the thrombosis and hemostasis field.” Five recipients are selected annually.

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Common cholesterol drugs could slow spread of breast cancer to brain

Common cholesterol drugs could slow spread of breast cancer to brain

A new study from the University of Notre Dame shows drugs used to treat high cholesterol could interfere with the way breast cancer cells adapt to the microenvironment in the brain, preventing the cancer from taking hold. Patients with breast cancer who experience this type of metastasis typically survive for only months after the diagnosis.

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Understand and Fight: Notre Dame researchers and the COVID-19 pandemic

Understand and Fight: Notre Dame researchers and the COVID-19 pandemic

The hero in Mary Shelley’s “The Last Man,” her second sweeping political science fiction after “Frankenstein,” is left alone in Rome, in a post-apocalyptic world. A global plague apparently took the lives of everyone else, yet he discerns a duty to forge ahead, no matter what.

Published in 1826, the novel mirrored Shelley’s life as she despaired at the loss of several of her loved ones. Her sister Fanny died by suicide. Her husband, the poet Percy Bysshe Shelley, drowned after a sailing accident. She lost another friend, the poet Lord Byron, to infection. Two of her toddlers died — one of malaria, and another from a fever. She kept a kind of plague journal, according to Eileen Hunt Botting

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Mary Galvin: It is more meaningful to ask what we can do to end intolerance

Mary Galvin: It is more meaningful to ask what we can do to end intolerance

Mary E. Galvin, William K. Warren Foundation Dean of the College of Science, addressed the issue of inequality with the students, faculty, and staff of the college:

Like many of you, I am deeply saddened by the recent killings of George Floyd, Breonna Taylor and Ahmaud Arbery and by this vivid reminder of the racism and inequality that persists throughout our country.…

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