News » Research

Science and Engineering Scholars Program propels students to success

Science and Engineering Scholars Program propels students to success

“This program is, wow,” said Chelsea Popoola, a math major who plans to attend medical school. The small classes allowed her to learn the material in a tight-knit environment. “I wish I had better words to explain how much this program has done for me. Whenever we need help with anything, there are many people willing to help.”

Read More about Science and Engineering Scholars Program propels students to success

WFCDD RFA Request for Applications-Now Open

The Warren Center for Drug Discovery invites new proposals for projects that are associated with drug discovery. In particular, projects associated with small molecule synthesis (libraries or molecular probes), hit validation, lead optimization, mid-sized scale up, assay development, protein purification, and ADMET screening. Any disease areas will be considered. Collaborative opportunities exist for the preparation of small molecules and/or computational-derived drug discovery via three cores: Chemical Synthesis & Drug Discovery, Computer-Aided Molecular Design, or Biological Screening and Development core. …

Read More about WFCDD RFA Request for Applications-Now Open

Notre Dame launches “Consider This!” a weekly webinar series discussing COVID-19

Notre Dame launches “Consider This!” a weekly webinar series discussing COVID-19

Author: Brandi Wampler

Starting in October, each Monday from 6 to 7 p.m. EST, coronavirus experts will discuss a new aspect or angle of the pandemic, such as epidemiology, food security, public health, racial inequities, testing, vaccines, and evidence used to inform decisions about opening schools, athletics, and businesses. 

Read More about Notre Dame launches “Consider This!” a weekly webinar series discussing COVID-19

How T-cell targets look in three dimensions may facilitate new cancer vaccines

How T-cell targets look in three dimensions may facilitate new cancer vaccines

T-cells, which hunt for traces of disease within other cells, work by identifying fragments of outsider proteins on a diseased cell’s surface and then go in for the literal kill.

With cancer, some of the mutated fragments of outsider proteins, called neoepitopes, can be recognized by T-cells and are ideal candidates for cancer vaccines. Unfortunately, those candidates are difficult to predict from genetic data alone.

 

Read More about How T-cell targets look in three dimensions may facilitate new cancer vaccines

Francis Castellino Receives 2020 ISTH Esteemed Career Award

Francis Castellino Receives 2020 ISTH Esteemed Career Award

Author: Mary Prorok

 

Francis J. Castellino

Francis J. Castellino, Kleiderer-Pezold Professor of Biochemistry and Director of the W.M. Keck Center for Transgene Research, has been selected as a recipient of the 2020 International Society on Thrombosis and Haemostasis (ISTH) Esteemed Career Award. This prestigious award is given to those who “have made significant contributions to the understanding, treatment and diagnosis, research and education in the thrombosis and hemostasis field.” Five recipients are selected annually.

Read More about Francis Castellino Receives 2020 ISTH Esteemed Career Award

Common cholesterol drugs could slow spread of breast cancer to brain

Common cholesterol drugs could slow spread of breast cancer to brain

A new study from the University of Notre Dame shows drugs used to treat high cholesterol could interfere with the way breast cancer cells adapt to the microenvironment in the brain, preventing the cancer from taking hold. Patients with breast cancer who experience this type of metastasis typically survive for only months after the diagnosis.

Read More about Common cholesterol drugs could slow spread of breast cancer to brain

Understand and Fight: Notre Dame researchers and the COVID-19 pandemic

Understand and Fight: Notre Dame researchers and the COVID-19 pandemic

The hero in Mary Shelley’s “The Last Man,” her second sweeping political science fiction after “Frankenstein,” is left alone in Rome, in a post-apocalyptic world. A global plague apparently took the lives of everyone else, yet he discerns a duty to forge ahead, no matter what.

Published in 1826, the novel mirrored Shelley’s life as she despaired at the loss of several of her loved ones. Her sister Fanny died by suicide. Her husband, the poet Percy Bysshe Shelley, drowned after a sailing accident. She lost another friend, the poet Lord Byron, to infection. Two of her toddlers died — one of malaria, and another from a fever. She kept a kind of plague journal, according to Eileen Hunt Botting

Read More about Understand and Fight: Notre Dame researchers and the COVID-19 pandemic

Dean Carlson: letter to graduate students on resolved issues

Author: Andy Fuller

Dear Graduate Students,

Let me start by thanking you for all that you are doing to continue your learning and research through these challenging circumstances.  And, thank you for reaching out to us as you have questions.  We are working through these, and a seemingly endless list of other issues that are unique for this time.  Below I provide an update on the issues that have been resolved.  Please keep asking and bringing to our attention any additional unique needs.  

Read More about Dean Carlson: letter to graduate students on resolved issues

Vural publishes cover article with graduate student Uppal in the Journal of Evolutionary Biology

Vural publishes cover article with graduate student Uppal in the Journal of Evolutionary Biology

Author: Shelly Goethals

Jeb V33 I3 Ofc

From subcellular structures to ecological communities, life is organized in compartments and modules specialized to perform only specific tasks, and not others. How does this division of labor come about, and what determines if species cooperate in a specialized or generalized fashion?

Read More about Vural publishes cover article with graduate student Uppal in the Journal of Evolutionary Biology

Researcher discovers key to how a cell wall promotes bacterial replication

Researcher discovers key to how a cell wall promotes bacterial replication

There are more bacteria in our mouths than the population of people on the planet, and no matter how clean our houses are, they’re brimming with various types of these micro-organisms. Still, despite bacteria’s ubiquitous influence, there’s so much that scientists do not know about them, according to University of Notre Dame chemist Shahriar Mobashery.

Read More about Researcher discovers key to how a cell wall promotes bacterial replication

Director's Message, Winter 2020

Director's Message, Winter 2020

Phillipstack1951

Phillip L. “Pete” Stack,

Graduation Day 1951, Dillon Hall

While I was working on my Master’s degree, diligently investigating the effects of ozone-induced free radicals on the structure and function of key proteinase inhibitors that prevent oxidative damage to lung tissue, my father was rapidly losing his battle with lung cancer. Phillip Leo ‘Pete’ Stack (Notre Dame class of 1951) did not really have much of a chance at survival in 1986, as the 5-year survival rate for lung cancer was only 13%. Pete joined the unlucky 83% who did not last anywhere near 5 years, and our family watched helplessly as this robust, hilarious, and highly cantankerous 6’6” tall 58-year-old transformed into a skeletal, bald, and weak shadow prior to his death. …

Read More about Director's Message, Winter 2020

Graduate students encouraged to apply to new fellowship program to advance research and communication skills

Graduate students encouraged to apply to new fellowship program to advance research and communication skills

Author: Brandi Wampler

The Notre Dame Institute for Advanced Study (NDIAS) and the Graduate School have launched a year-long fellowship program that aims to help students accelerate their dissertations, develop their research communication skills, and cultivate professional and scholarly networks, all within the context of a vibrant and supportive intellectual community.

Read More about Graduate students encouraged to apply to new fellowship program to advance research and communication skills

Notre Dame announces the Center for Network and Data Science

Notre Dame announces the Center for Network and Data Science

Author: Brandi Wampler

At the University of Notre Dame, the Center for Network and Data Science (CNDS) – formerly known as the Interdisciplinary Center for Network Science and Applications (iCeNSA) – brings together faculty and other researchers to generate fundamental transformative advances in artificial intelligence (AI), data science, and network science with interdisciplinary applications in biological sciences, neuroscience, molecular synthesis, health and wellbeing, network science, foundations of computing, physical and transportation systems, and social systems. 

Read More about Notre Dame announces the Center for Network and Data Science