News » Research

Francis Castellino Receives 2020 ISTH Esteemed Career Award

Francis Castellino Receives 2020 ISTH Esteemed Career Award

Author: Mary Prorok

 

Francis J. Castellino

Francis J. Castellino, Kleiderer-Pezold Professor of Biochemistry and Director of the W.M. Keck Center for Transgene Research, has been selected as a recipient of the 2020 International Society on Thrombosis and Haemostasis (ISTH) Esteemed Career Award. This prestigious award is given to those who “have made significant contributions to the understanding, treatment and diagnosis, research and education in the thrombosis and hemostasis field.” Five recipients are selected annually.

Read More about Francis Castellino Receives 2020 ISTH Esteemed Career Award

Common cholesterol drugs could slow spread of breast cancer to brain

Common cholesterol drugs could slow spread of breast cancer to brain

A new study from the University of Notre Dame shows drugs used to treat high cholesterol could interfere with the way breast cancer cells adapt to the microenvironment in the brain, preventing the cancer from taking hold. Patients with breast cancer who experience this type of metastasis typically survive for only months after the diagnosis.

Read More about Common cholesterol drugs could slow spread of breast cancer to brain

Understand and Fight: Notre Dame researchers and the COVID-19 pandemic

Understand and Fight: Notre Dame researchers and the COVID-19 pandemic

The hero in Mary Shelley’s “The Last Man,” her second sweeping political science fiction after “Frankenstein,” is left alone in Rome, in a post-apocalyptic world. A global plague apparently took the lives of everyone else, yet he discerns a duty to forge ahead, no matter what.

Published in 1826, the novel mirrored Shelley’s life as she despaired at the loss of several of her loved ones. Her sister Fanny died by suicide. Her husband, the poet Percy Bysshe Shelley, drowned after a sailing accident. She lost another friend, the poet Lord Byron, to infection. Two of her toddlers died — one of malaria, and another from a fever. She kept a kind of plague journal, according to Eileen Hunt Botting

Read More about Understand and Fight: Notre Dame researchers and the COVID-19 pandemic

Dean Carlson: letter to graduate students on resolved issues

Author: Andy Fuller

Dear Graduate Students,

Let me start by thanking you for all that you are doing to continue your learning and research through these challenging circumstances.  And, thank you for reaching out to us as you have questions.  We are working through these, and a seemingly endless list of other issues that are unique for this time.  Below I provide an update on the issues that have been resolved.  Please keep asking and bringing to our attention any additional unique needs.  

Read More about Dean Carlson: letter to graduate students on resolved issues

Vural publishes cover article with graduate student Uppal in the Journal of Evolutionary Biology

Vural publishes cover article with graduate student Uppal in the Journal of Evolutionary Biology

Author: Shelly Goethals

Jeb V33 I3 Ofc

From subcellular structures to ecological communities, life is organized in compartments and modules specialized to perform only specific tasks, and not others. How does this division of labor come about, and what determines if species cooperate in a specialized or generalized fashion?

Read More about Vural publishes cover article with graduate student Uppal in the Journal of Evolutionary Biology

Researcher discovers key to how a cell wall promotes bacterial replication

Researcher discovers key to how a cell wall promotes bacterial replication

There are more bacteria in our mouths than the population of people on the planet, and no matter how clean our houses are, they’re brimming with various types of these micro-organisms. Still, despite bacteria’s ubiquitous influence, there’s so much that scientists do not know about them, according to University of Notre Dame chemist Shahriar Mobashery.

Read More about Researcher discovers key to how a cell wall promotes bacterial replication

Director's Message, Winter 2020

Director's Message, Winter 2020

Phillipstack1951

Phillip L. “Pete” Stack,

Graduation Day 1951, Dillon Hall

While I was working on my Master’s degree, diligently investigating the effects of ozone-induced free radicals on the structure and function of key proteinase inhibitors that prevent oxidative damage to lung tissue, my father was rapidly losing his battle with lung cancer. Phillip Leo ‘Pete’ Stack (Notre Dame class of 1951) did not really have much of a chance at survival in 1986, as the 5-year survival rate for lung cancer was only 13%. Pete joined the unlucky 83% who did not last anywhere near 5 years, and our family watched helplessly as this robust, hilarious, and highly cantankerous 6’6” tall 58-year-old transformed into a skeletal, bald, and weak shadow prior to his death. …

Read More about Director's Message, Winter 2020

Graduate students encouraged to apply to new fellowship program to advance research and communication skills

Graduate students encouraged to apply to new fellowship program to advance research and communication skills

Author: Brandi Wampler

The Notre Dame Institute for Advanced Study (NDIAS) and the Graduate School have launched a year-long fellowship program that aims to help students accelerate their dissertations, develop their research communication skills, and cultivate professional and scholarly networks, all within the context of a vibrant and supportive intellectual community.

Read More about Graduate students encouraged to apply to new fellowship program to advance research and communication skills

Notre Dame announces the Center for Network and Data Science

Notre Dame announces the Center for Network and Data Science

Author: Brandi Wampler

At the University of Notre Dame, the Center for Network and Data Science (CNDS) – formerly known as the Interdisciplinary Center for Network Science and Applications (iCeNSA) – brings together faculty and other researchers to generate fundamental transformative advances in artificial intelligence (AI), data science, and network science with interdisciplinary applications in biological sciences, neuroscience, molecular synthesis, health and wellbeing, network science, foundations of computing, physical and transportation systems, and social systems. 

Read More about Notre Dame announces the Center for Network and Data Science

Ptasinska appointed Editor-in-Chief of European Physical Journal D: Atomic, Molecular, Optical and Plasma Physics (EPJD)

Author: Shelly Goethals

Ptasinska Thumbnail

The European Physical Journal D: Atomic, Molecular, Optical and Plasma Physics (EPJD) has announced that Prof Sylwia Ptasinska of the University of Notre Dame has been appointed as an Editor-in-Chief for EPJ

Read More about Ptasinska appointed Editor-in-Chief of European Physical Journal D: Atomic, Molecular, Optical and Plasma Physics (EPJD)

Stack paper featured in special journal issue on cancer research

Stack paper featured in special journal issue on cancer research

A paper published in 2017 from M. Sharon Stack, the Anne F. Dunne and Elizabeth Riley Director of the Harper Cancer Research Institute at the University of Notre Dame, has been selected as a featured article in the special virtual issue of the Journal of Biological Chemistry that highlights cancer research. 

Read More about Stack paper featured in special journal issue on cancer research

Notre Dame's infrastructure for machine learning to be expanded

Notre Dame's infrastructure for machine learning to be expanded

Author: Cheryl Schairer

Li Jun Image

Biophysics faculty members, Jun Li, associate professor in the department of Applied and Computational Mathematics and Statistics and Olaf Wiest, professor in the Department of Chemistry and Biochemistry, are two of four College of Science faculty members awarded a two-year grant through the National Science Foundation (NSF), that will establish the creation of a pool of new computer nodes dedicated to providing researchers with new high performance technology for quicker speeds.

The University of Notre Dame is bolstering cyberinfrastructure that will support greater access to machine learning.

Read More about Notre Dame's infrastructure for machine learning to be expanded

Super Resolution Ghosts: ND Engineer discovers new imaging methods for cell research

Super Resolution Ghosts: ND Engineer discovers new imaging methods for cell research

During his postdoctoral research, Notre Dame electrical engineer Scott Howard wanted to produce more precise images of the activity within a cell by increasing the power of the microscope’s laser.

When he experimented with different power levels, he discovered that his computer was receiving an extra copy of image data.

“When you push the lasers up too high, it would scramble the data because the different parts inside the cell get saturated and can’t absorb any more light,” Howard said. “But I was getting this extra copy that I called a ‘ghost image.’”

Read More about Super Resolution Ghosts: ND Engineer discovers new imaging methods for cell research

Three Indiana research universities to collaborate with industry to solve critical measurement science challenges in new NSF-funded center

Three Indiana research universities to collaborate with industry to solve critical measurement science challenges in new NSF-funded center

Author: Brandi Wampler

Powering everything from the development of new drugs and medical devices to the detection of dangerous chemicals, measurement science is a multi-billion-dollar industry that is key to both U.S. and international economies. With a grant from the National Science Foundation (NSF), researchers from the University of Notre Dame, Indiana University, and Purdue University have formed a new center that will work to solve ongoing and emerging industry-relevant challenges in measurement science. 

Read More about Three Indiana research universities to collaborate with industry to solve critical measurement science challenges in new NSF-funded center

New collaboration led by Notre Dame leverages Data Revolution to solve current challenges in chemistry

New collaboration led by Notre Dame leverages Data Revolution to solve current challenges in chemistry

Author: Tammi Freehling

Olaf Wiest 250 pixels square

Olaf Wiest, professor in the Department of Chemistry and Biochemistry, will direct The Center for Computer-Assisted Synthesis (C-CAS). “This will significantly accelerate progress in drug discovery and materials science where such molecules are critical to fundamental research,” Wiest said.

Read More about New collaboration led by Notre Dame leverages Data Revolution to solve current challenges in chemistry